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Using two separate drugs to shed weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people that go through it you should err assisting caution and allow FDA do its job and demand some investigation be done so the public knows the side effects and dangers of the medications before we drive them. Keep in mind that drug companies will be in business to earn money and that they would say almost anything to keep people on his or her medications. Researchers discovered that participants taking this drug for any year, dropped excess weight within 4 weeks and have kept the load off through the 56 weeks of the study. Contrave is a combination of the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which are made up of several active ingredient, that might make them more efficient and safer. Combo-pilling may be the newest fad or also the newest ahead under scrutiny and for that reason it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular is the fact that as of right now there are no long term prescription weightloss pills that have been approved by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug could also raise blood pressure levels and heartrate, and must not be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must stop used in patients with uncontrolled high blood pressure levels, as well as by you are not heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients using a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients on the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking. 
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