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Using two separate drugs to shed weight can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the people who go through it you ought to err to the side of caution and allow FDA do its job and demand some investigation be done in order that the public is aware of the side effects and risks of the medications before we bring them. Keep in mind that drug companies come in business to generate money and that they would say everything to keep people on the medications. Researchers found that participants taking this drug for the year, dropped excess weight within a month and have kept the load off during the entire 56 weeks from the study. Contrave is often a combination in the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which are made up of more than one active ingredient, which can make them more effective and safer. Combo-pilling is the newest fad or in addition to this the newest in the future under scrutiny and so it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular could be the fact that by right now there aren't any long term prescription weight loss supplements that have been authorized by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug also can raise blood pressure and heartrate, and mustn't be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must 't be used in patients with uncontrolled high blood pressure, along with by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients using a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients on the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. 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